Current Issue Volume 1 Issue 2

Open Access Research Materials Science
Article IconPossibility of Phase Transition in Mechanical Metamaterials
Julian Plewa*
ORCID
Abstract Views: 44 ⬇ Downloads: 112 DOI: 10.212333/goajs.v1i1.1016
Abstract: Based on the available knowledge from numerous simulation studies regarding the occurrence of metamaterial phase transition, structures were produced that exhibit a real auxetic-non-auxetic transition. The occurrence of this transition was possible thanks to the modified structure of rotating rectangles, showing significant dimensional changes....
Open Access Review Proteomics
Article IconAdvances in Single-cell Proteomics
Jin-Tao Li*
ORCID
Abstract Views: 87 ⬇ Downloads: 111
Abstract: Nowadays, single-cell proteomics emerges and applied for some critical realm both scientifically and medically. In single-cell analysis, biological variability can be attributed to individual cells, their specific state, and the ability to respond to external stimuli, which are determined by protein abundance and their relative alterations.....
Open Access Review Neurology
Article IconA Keratan Sulfate: An Electroconductive Proton Capture Glycosaminoglycan Regulator of Neuronal Membrane Polarization, Ion Fluxes, Neuronal Activation and Neurotransduction
James Melrose1,2*
ORCID
Abstract Views: 68 ⬇ Downloads: 90
Abstract: This study describes keratan sulfate (KS), a multifunctional electroconductive glycosaminoglycan, and it’s participation in electrochemical processes that regulate neuronal activity. Neuronal cells are highly responsive to electrical stimulation and this is an intrinsic evolutionary property of this cell type.....
Open Access Review Clinical Medicine
Article IconNikethamide Alleviates Low SpO2 during Gastrointestinal Endoscopy under Total Intravenous Anesthesia with Propofol Combined with Sufentanil: A Randomized Controlled Trial
Lian Xin*
ORCIDZheng-feng Gu, Yi-ling Qian, Han-zhe Sun, Wei Wang, Shuai Pan, and Jin-long Lin
Abstract Views: 51 ⬇ Downloads: 60
Abstract: Background: Gastrointestinal Endoscopy under Total Intravenous Anesthesia (GETIVA) is used for gastroin-testinal disease investigation. Total intravenous anesthesia with propofol and opioids is usually applied but could result in respiratory depression or low oxygen saturation. This study aimed to test the effectiveness of nikethamide (respiratory stimulant) for alleviating low oxygen saturation induced by combined propofol and sufentanil use during GETIVA......